I shall add to the discussion...
Consider the Lake LA-4 Amphibians, whose engine is pylon mounted entirely above the fuselage of an otherwise common layout aircraft. The H stab is logically located in the propwash, but other than that aid to pitch control, no special provisions seem to have been made to offset the affects of the engine/prop mass way up high. The plane flies very well, with power changes only slightly affecting pitch (mostly when operating on the water - but entirely controllable). Having done extensive flight testing including stalls, spins, and balked approaches, I can attest that there is no negative affect from the high C of G. Even the fuel is not in the belly! A well designed aircraft in this regard.
Pilot DAR