Tangential, but related:
The DC-10 & MD-11 have two donks low, one donk high -- and I am told that a #2 engine failure causes a worrisome nose-up pitch. It can readily be trimmed out, but it's a handful for a short time.
Also - 30 years ago a thoughtful F/E came up with a simple drag-reduction scheme for the DC-10: Run #2 engine at reduced thrust in cruise, so the stab won't have to work so hard fighting the nose-down moment of the high engine. It would have worked, were it not for the efficiency falloff of gas turbines at reduced throttle: thrust falls off faster than fuel burn. So, you lose more than you gain.
