An answer not really explained above...
An engine failure at rotate/V1 loses a 146 25% of thrust, a "126" 50%. If it now needs to climb over an obstruction, the twin will have a large payload penalty, or the twin needs much bigger (and expensive) engines to start off with.
Unfortunately, while there are routes (LCY) where this is/was needed, not enough to base/justify a whole design on...
NoD