On the assumptions that you will never get rid of the restriction and that thus single crew commercial operations are forbidden....
Did the CAA put the restriction on your medical certificate, the licence itself or on both.
If the endorsement is on your licence, it will probably be noticed at interview time.
If it's only on your medical certificate it almost certainly won't be.
If the endorsement is on your licence, you could go back to the medical section and ask them to have it removed from the book itself. You might then have to pay a fee for a new page without the offending remark. The CAA medical section have always seemed to be pretty good about this. You would need to talk with one of the CAA doctors at LGW, perhaps at the next review?
Plenty of people have two crew only endorsements on their medicals. Kidney stones for example may lead to such a state of affairs.
If you are interviewing for a two crew operational job, there shouldn't be a problem and indeed, since you hold the requisite Class 1 certificate, it might be said that your personal medical problems are no one else's business.
If the endorsement is only on your medical certificate, it is obviously up to you as to whether or not you divulge this information. I suppose that if a company were to hire you without your informing them of this restriction, they could subsequently fire you on the grounds of non disclosure? But I rather fancy that an airline would have found other, less contentious means of getting rid of you if they wanted to.
You might think it an idea, at your next review, to ask the CAA doctor whether he thinks you should disclose such information at an interview. I suspect that he will tell you that the matter is one of personal confidentiality.
You might also ask the CAA for what I think is called the protocol schedule. It's a paper in which they outline exactly what you cannot, or can do with that restriction. For example, in instruction, if you have that restriction, you may indeed give instruction, and to a pupil who has completed his first solo. What you cannot do in this theatre of operation, is to take up a student who could not land the aircraft if you were suddenly incapacitated. So advanced twin training is in the loop, initial twin training would not be.
Hope that the above spiel is of some use and good luck.
