http://www.flightglobal.com/articles...-take-off.html
Pilots of the Kalitta Air Boeing 747-200 freighter destroyed after overrunning at Brussels rejected the take-off at about the same time as air traffic controllers observed a fire in one of the aircraft’s two right-hand engines.
that seems very plausable - aircraft at V1 or just after has a fire alert and rejects the take - off, leaving little breathing room for slowing down at near rotation speed for a heavy loaded freighter.
will be a brown trousers moment for any freight dog to suddenly lose an engine at a critical time.