A colleague told me some great advice.
"Always look for your next job while you're still happy in your current job."
This advice was especially relevant in Australia as your first couple of jobs would entail flogging around in the bush flying singles and twins.
However, whether your goal is wide bodies for Cathay or Emirates or lo-co B737s or A319s, plan your career wisely and with the above top tip in mind. (As usual, be flexible)