That's a tough one. On one hand, I'd like to think you'd have a fair chance. I don't think an airline would use you as a
PR poster child to show how egalitarian they are though. The public would be split in whether or not they would accept this if they knew airline XYZ had a pilot with such a disability. If you have a good enough prosthetic to hide this in the interview and sim check, this would give the airline some re-assurance that the passengers are not likely to notice. If you don't reveal it until after these hurdles, you take the chance of alienating them. There's always the next one though.
Another thing to research though is whether or not it will hinder your post employment training, such as using the emergency slides and any swim qualifications needed.