You'll oft hear the phrase "first to worst". In this industry, one airline may be tops one year and the next, due to Mgt. changes, poor planning or a general lack of strategy, may be the least sought after. Also, just because an airline is number 1, doesn't necessarily guarantee the QOL expected and deserved of her pilot group; vice-versa holds true, as well. Ask that question again a few months before you meet the minimum requirements for a given airline, and it will, unfortunately, still be a shot in the dark. So it is with this industry.