It's been done before, several times. How you approach it makes all the difference. Three examples I can quote from personal experience.
One guy kept his previous experience quiet. No one knew he had 500 hours during to the course, he only came clean on graduating. Interestingly, his experience didn't show and he was the first to admit that it didn't help much with the exception of instrument flying.
Another guy was an experienced helicopter pilot before RAF flying training. He was a star and went on to fly fast jets despite the RAF thinking his experience would make him want to fly military helicopters. He was there to learn new skills and was humble.
The third guy was an instructor with quite a lot of experience, let everyone know and frequently took it on himself to tell his instructors how they could improve their instructional technique! We had to stop him briefing his coursemates with his own techniques - which he knew were better! He was a complete pain in the @rse and all the instructors hated flying wih him. With his attitude, he was lucky to get through especially that wasn't even that good as a pilot!
It's not a barrier and how you approach it is up to you. But I would suggest the second guy's approach as being the most successful.