I use iTunes for the stuff that goes on the iPod, mainly because that's what came with it. It also installed Quicktime, but I've got that more or less corralled and out of the frame. It updates those two about once every six weeks, which I can live with.
However, I'm getting heartily sick of the daily prompts to "update" Safari. There is no Safari on this PC to update - I think this is an attempt to hijack my browser function. So I'm seriously considering dumping the whole Apple package. That's just too sneaky.
Unless I can find a way to stop the prompts for Safari, I think something has to go. Maybe I just need to kill the Apple Software Updater - I don't think I need to update iTunes any more, since it works.