Fab, in the UK it is an offence under the ANO for anyone to be drunk on board an aircraft.
If these four were as bad as is quoted (and it wouldn't surprise me one bit) the check-in staff should have refused to check them in. That having been missed, the security staff should not have allowed them through, gate staff should have not have allowed them into a dangerous are of the airport, and the cabin crew should have refused them.
Damn the slots. Get their bags off.
They can fly when they're sober enough. And all tour operators should be made aware that their customers will be left behind if they're not fit to travel.
Not only would they be unable to evacuate themselves in the event of an emergency, they would also hinder sober passengers.
Furthermore, they are far more likely to be offensive and violent during the flight.
They will not find a seat on any aircraft of mine.