It's just a matter of managing one's life appropriately.
Didn't I used to work for you? I recall a memo once about "compartmentalizing your fatigue"......
As for doctors, controllers, et al: slight difference in the magnitude of the downside risk.
(Have you ever heard the difference between ham and eggs? The chicken is involved, but the pig is committed....)
I'll compare the relative fatigue of doctors and pilots when doctors die if their patients die. Hell, I'd settle for them losing their licenses if they make a fatal mistake.