I disagree with dan and setright. I fly the -200 and enjoy every minute.
This is the last 'true' airplane out there - this kind of airplane is why I became a pilot. If I wanted QOL, I would become something else. Besides, the quality of living everyone is looking for is different. For some it is the opportunity to be home every night, despite flying 4-6 short hops in a 320 or 737, not even having the chance to enjoy the destinations the fly into.
For others, crossing oceans and deserts in a 380 ton machine, with the option to spend a couple of days at the far corners of the world is the quality of living they enjoy.
As far as eu operators, there's cargo b, girjet, air atlanta. You can also try your luck at jalways, based at HNL, or air india, both flying the -300.