I would steer clear of the two beacons. That gap between Heathrow, Luton and Stansted can be very congested and I rather suspect that a lot of people hop VOR to VOR...with the low class A ceiling above you it is potentially a collision point. Ask Luton for a zone transit...it means you don't have to worry about infringing and you'll be safer inside CAS.
If the weather is good enough to go over Boscombe MATZ then do...then just route direct to Compton Abbas from there. If you can't go through the overhead of either Boscombe or Middle Wallop then most people route via Chilbolton...which is easy to identify because there is a satellite dish there.
There is a lot traffic in the Boscombe area...from the four busy airfields inside the CMATZ but Boscombe (126.7) are used to dealing with it.
Just watch out for Apaches hiding behind hills!
If at the weekend route through Thruxton overhead, remain above Boscombe ATZ because it might be active.