It is probably not the best pilots aircraft that Boeing have built (most say the B727 was) but it will do the job safely and a lot faster than the classic.
It has got icing issues but nothing that can't be delt with using the proper drills.
I like flying the aircraft and have no issues with it at all but it is not the best aircraft to hand fly but is far from being the worst. I have landed the aircraft in a quartering 28G48KT cross wind the speed acording to the PFD speed tape was all over the place but it is over sensitive, in gusty conditions it is best to use the standby ASI as this is better damped and avoids you chasing the speed.
As for hand flying airliners the Lockheed L188 Electra is the best I have flown by far.