I haven't beenthere in a few years, but I remember it being good practice to turn on the autopilot as soon as possible after takeoff, as they will issue a lot of frequency changes, and one leveloff follows another.
Not a good place for manual flying...
And request descent early, as above posts have indicated, also because of the many frequency changes, it adds up flying a couple miles level before getting the next clearance.
Have fun
Nic