No one has got as close as the originals to solving it.
Apart from Capt. Eric Genotte, F/O Steve Michielsen and F/E Mario Rafoil who actually managed to land thier A300 (OO-DLL) after losing all hydraulics due to a missile attack over Baghdad
2003 Baghdad shootdown incident 
As for the original question, yes sometimes we will be exposed to multiple failures or very abnormal system operation. Often the most bizarre stuff is experienced after a Sim session has officially finished (In respect to the training syllabus) and there is a little time to spare. No point wasting paid-for simulator hours!