I had an Epson DX4850, and unhappy with the price of genuine cartridges tried an alternative ("Inkrite" if my memory serves me correctly). I can't honestly say whether there was any difference in colour rendition, but one problem immediately showed up - EVERY time I pressed "Print" I got a warning - "Epson has detected that you are using non-genuine inks".
Some while later it stopped printing red, and despite trying the head cleaning utility several times got nowhere with it. Fortunately it was still under guarantee and I still had some original (used) cartridges to put in.
The local Epson agent also had to admit defeat, and I was given a service exchange unit, which gave me no end of problems trying to get the P.C. to recognise it. (Another story)
I've decided to stick to genuine ones for now.... No doubt just what the manufacturer intended.