Get to a doctor!
However, in the meantime analyze your food intake very carefully. Look for something that is causing this reaction. By this I mean look to see if there is anything new that you are taking, such as a type of wine or even strong coffee. Some wine is straight out of the chemistry lab these days!
Are you on any new medication?
Your weight is a serious issue, but don't try to correct that too rapidly until you have a clear indication of what is wrong. Diet, but with great caution. Try to get back to an intake that's exactly as it was when you were not showing these symptoms.
Be very mindful of other factors such as a reaction to substances touching your skin...petrol, or even stuff normally as innocuous as washing-up liquid for instance. Do you have any itching on your hands? Also, be sure that you are not breathing in anything that you may be reacting to.
Just get rid of all the variables so that your doctor can start with a level playing field.
What was your resting heart-rate before you noticed these other symptoms?