The scenerio you describe sounds like something you would see in a sim. The odds of all those conditions coming up in real life are remote to the extreme. Of course that doesn't mean it can't happen. In the sim you are trying to get though the scenerio, so as long as you don't waste too much time and get the airplane on the ground in one piece there should be no problem. In real life you don't know what is happening out on that wing so you should get the plane on the ground in the absolute minimum time. If you have time to talk to the F/A and pax you are taking too much time. Just tune the ILS and get to it quick. Do not use minimums, the autopilot will find the runway. Max braking to a stop and evacuate.
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