If it's a matter of choosing between SEN and LYX, then they have very similar runway lengths anyway.
My adage would always be 'get established at the best location for your initial operation in order for that to be successful' and 'never have entrenched ideas as to how your operation might grow - be prepared to change your plans as the reality of the initial operation takes shape'.
After all, there is no point choosing somewhere like MSE just because it has a long runway, which may or may not be useful to you in the future, if it's location will be a hindrance to firmly establishing your commercial viability in the first place.
I wish them well whatever they choose to do.