It is not for the feint hearted, some of the guys I worked with never truly got used to their job. You have to be on the ball to say the least, an accident is a very real possibility if you dont follow the rules and exercise good airmanship. Be prepared, rehearsing an engine failure drill just once every 6 months would be foolhardy, for example, probably all the aircraft you fly will be significantly older than you! As said above, NO is usually not a good answer when there is a four grand job on the phone, you better be able to back up your decision with the weather reports that rattled your sphincter and influenced your decision not to fly! Make sure you know where the alternate air is and hope that the de-ice system does'nt look like a fifty year old inner tube thats been repaired a hundred times!! Air charter is not for everyone, but its an invaluable tool for progressing up the aviation ladder. Sometimes I wish I was back in the hotseat, great days!