I dont think there is a right or wrong answer to this debate ....
The way I would deal with a main deck fire EICAS would be very different depending how far away I was from a usable runway.
A friend recently said to me that compared to PAX 74's we are at an advantage ... upon asking - why? He said everything on a 744F is checked for dangerous goods HAZMAT etc and packaged accordingly. In the hold of a PAX a/c all sorts could be in those suitcases ...
Also on a the main deck of a 744F their is very little wiring (ie. IFE) to spark off a fire ....
The weak link in cargo is the load controllers and shipping agents, trusting the packaging and loading UN instructions have been adhered to.