I think it is VERY realistic.. On FS2000 you take off from Heathrow, get the Autopilot set up, Have a nice cup of hot chocolate, get comfortable in your seat, set the alarm clock for say 7hrs later and have a nice relaxing sleep..
You wake up refreshed and make a slick landing at O'Hare. Just like the real thing!!!!
At weekends I fly Heathrow to Bangkok as I like to sleep in late...