The question, years in the future, will be whether you are willing to work in the right seat of a jet for about minimum wage, after spending about $20,000 on the multi-, instrument, commercial and instructor ratings and later finishing a very intense training syllabus at your first airline.
The regional airlines will do a larger fraction of US domestic flying, some of which is still flown by 737s and DC-9s. Many of the pilots who are already at regional airlines will find no openings at the US major airlines, because they are already doing flying, i.e. IAH-MCI, CLE-EWR, MEM-PHL, all of which was flown years ago by 100-seat narrow body mainline jets (at major airline salaries). Some majors are trying to switch to mostly trans-continental, international city pairs.
The fact that many CRJ, and ERJ pilots have no 4-year degree will make no difference, unless many years later they are somehow extremely fortunate and receive an invitation to interview at a career company (with quality leadership...not data-crunching, self-centered nerds who count the pilots as only a liability...) such as Southwest or Fedex, maybe a good foreign airline.