The only aircraft on MSFS that I have real experience of is the C172 and the Baron (a little).
To be honest, I have to say that, provided they are correctly trimmed, they seem remarkably similar to the real thing. The problem is that there is less incentive to trim on FS because you don't get stick loads (maybe you can if you have a good force-feed back stick). If you don't trim, then landing can be difficult, just like the real thing.
I used MSFS to help sort out my crosswind landings using the C172 and it was extremely helpful for wing down technique. Perhaps not so good for crabbing as it is quite difficult to judge the flare without the peripheral vision one normally gets.