With large geared piston engines, the propellor should not 'drive' the engine for two very distinct reasons...
1. Accelerated master rod bearing wear.
2. Piston ring float (chatter).
Number one clearly applies to radial engines, number two to both, radial and opposed.
Keep in mind that these two conditions are present during landing, and this is not a problem.
However, prolonged flight at low manifold pressures (and/or BMEP) with higher RPM's should be avoided.
For further information on large piston engines consult
www.enginehistory.org
Pay particular attention to the subject of bifler pendulum dampers, and the bushings these ride on, as mishandling the throttle on these large engines is NOT good.