Feels better, flies better, lands better.
Longer by 6.9m so you need to steer more to the outside of turns to keep mainwheels near the centreline of taxiways.
Keep take-off rotation rate steady 3 degrees/sec - don't snatch it off and avoid sudden increases off pitch rate at 8 degress - you'll bang the tail.
Don't get slow on approach or any where near 9.5 degrees nose-up in the flare - you'll bang the tail again.
If heavyweight on take-off you need to be careful around F+1 limit as S speed can be above 210kts - best to have the A/P engaged, it's tuned for a two-stage acceleration to hold the aircraft at 215kts until the flaps are in.
F2 limits same as F1+F, 215kts; F3 195kts; F Full 190kts.
Some technical differences eg jet pumps for the centre tanks.
That's about it.