What do you mean by "all the security I have in place"?
Surely you're not referring to Spybot and AdAware?
Try this:
http://www.superantispyware.com/ S&D and AdAware have they're uses, but as primary malware scanners...well, they've been overtaken, would be a nice way to put it.
Other goodies: AVG Antispyware (30 day trial of resident) Asquared, and SpywareTerminator (Free resident antispyware with HIPS. Brilliant.)