The danger in splitting up a trip (esp. a VFR trip) into three parts, with overnight stays, is that the weather is unlikely to hold up.
If I was going to Prague VFR I'd do it in one day. Most spamcans can do it in two legs.
A TB20 can do Prague and back, from say Southampton, without landing (just!).
What this means is that you can get TAFs and METARs all the way along the route, and that is the most reliable weather you will ever get.