To be honest, haven't used NTServer before, only straight NT4 (network + workstation).
However, NT4 will set up its own limited-size file system (NTFS) and that's all it will recognise.
Most administrators using large drives will partition the drive, put Windows on C: and dual boot with NT on a separate partition, but initial configuration may not be straight forward for a lot of people.
I believe Windows 2000 will allow NT4 to see each others file systems, but best have a guru chip in here with the real low down.
Apologies as this aint much help :-)
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Me, sweat? I'm that cool, it's condensation.