The ideal ones for that sort of route would be VLM or Scot Airways.
Flybe stopped operating the Jersey-London City and the Isle Man services when the last of the smaller Dashes left the home meaning the 300s and 200 Dashes they operated in the earlier days, which seem a long time ago now.
If a service does start it would have to be morning and late afternoon or early evening to try and work.
Some of the problems would be getting the slots at London City as the service would require some prime time ones Monday to Friday.