Decision making.
A very wise pilot once taught me how to make a decision.
Ask yourself, in this order:
--Is it safe?
--Is it legal?
--Is it comfortable for the passengers?
To the new pilot, "legal" often equates to "safe," but with experience you'll find many situations where it's legal to fly but good judgment persuades us otherwise. High winds could be one of those situations.
When flying in high winds, two of the most important considerations (one as alluded to by Bearcat) is whether or not the wind is "steady state" or not.
In other words, I stand a much better chance of making a "stabilized approach" in a *steady* 30 knot wind than in a *gusty* 30 knot wind.
Windshear and turbulence just make our jobs even more difficult, if not impossible, under extreme conditions.
The other consideration, in my opinion, when flying in high winds, is whether or not the runway is contaminated. I have been in a situation (albeit in lighter aircraft) where the wind was straight down the runway and the runway itself was in good condition but the taxiways and ramps were so icy it proved to be impossible to taxi as the airplane wanted to "weathervane" into the wind. In that situation the only option was to shut down and get towed to parking.
So it's hard to completely answer your question because, basically, every day is a new day, and sometimes we feel up to it and sometimes we don't. But with experience comes judgment (usually!) and we learn to evaluate the "character" of the wind, the significance of day or night, good visibility or poor, good braking action or poor, as well as the condition of our airplane (Are there any deferred maintenance items that may affect our performance on the runway?).
I hope that answers your question (somewhat).