I asked this simulator question of the CAA 18 months ago and at the time was informed that the initial checkride could not be done in the simulator.
Once you have the Instrument/ATPL portion completed types could be added via simulator training.
You could of course do the checkride in the S76 aircraft, without training, as you have 500 hours on type. Subject to having 1000 hours multi pilot.
The ATPL requirements that you are looking for are in the LASORS Section G3.5
http://www.caa.co.uk/docs/175/SECTION%20G.pdf