Our (-300) procedure is not much different than "SAy Again"'s..
We depart in "Go-around" mode, and once we get our flaps up and bleeds on (usually around 800-1000' for a flap10 departure), we set IAS to 135 with both engines running. (Vfto if one is out.) Passing MSA or VMC conditions, we continue at 165.
Works fine for us, and the normal practice is to pitch-sync to roughly 135kts before commanding the PNF to select IAS/135 and engaging the autopilot.
As for the -100, there are certain departures where v2+10 is required even with both engines running. Places your nose awkwardly high, but keeps your turn radius to a minimum.