Plenty of scientific answers already, which is great. I doubt you'll find solid figures, so people's impressions will be your likely best answer -- alas, a notoriously poor way of evaluating anything in my opinion.
I used to fly a 3-blade 182 and now a 2-blade 182. I think the 3-blades looks better, take-off performance seemed slightly better and ground clearance is a good few inches more. All the differences seem fairly minor to me. Certainly I wouldn't change one for the other unless it was time for a new prop anyway.