Am sure that the crew rest period will be examined very seriously and to great detail.
Sad really, very sad.
(By the way, I have a very good friend who is in ATC at Lexington, I learned from him 4 hours ago that the aircraft departed on 26. No, he was not the controller on duty, but one of his best friends was the one on duty. I refrained from making any comments on runway 26 until the NTSB confirmed that the aircraft did in fact takeoff, or rather attempted to take off, on runway 26. I will make no other comment about the controller except the fact he is taking this horrible accident very hard.)
God bless all involved and pray for the First Officer.