In the GoM, the limit is max certificated gross weight. We just load up to max gross and head out (or in). The only model I'm aware of that won't cruise at MGW OEI is the BO105. We certainly aren't doing Cat A takeoffs or landings, but then you said you have unlimited runway available. There certainly are altitudes at which this doesn't apply, but at sea level we don't often need to consider altitude power restrictions.
Considering the places we operate from, an engine failure on takeoff will likely result in bent metal, but we're flying around a quarter million hours per year, down considerably from the past few decades where one company could fly that much, and
AFAIK there have been zero accidents resulting from engine failure on takeoff. That isn't killing us, flying into the water/terrain/platforms with both engines operating is.