The sad fact is that a hull loss due to fatigue will be attributed to 'human factors', or just plain old pilot error with the true reason for the disaster quietly covered up. Never underestimate the ability for airlines to pull strings, lie and cheat their way out of taking responsibility. We could build a list which would have no definite beginning and sadly no end but would include Erebus, Joburg and Bahrain. Two hull losses and one very close shave with very few lessons publicly learned. Oh yes the causes were identified but the systemic failures that 'set the scene' were glossed over.
So while we shout from the rooftops about how the airlines will rue the day they pushed us to the limits, the reality is that they probably won't be held accountable.