B747, double engines lost...

[ckhy]

For a B747-200, or just 747s in general, if engines 3 and 4 were lost (seperated from the wing totally), what systems would be affected?

For a start i know the hydrualics and hence control problems, but what are the other ones because serioulsy i cannot think of anything else .

Any input would be greatly greatly greatly GREATLy appreciated.

Cheers

and safe flying