It's very easy to miss a deflated tyre on the 145. This leaves the other tyre to do all the work and it wont last long.
Our company always changes both wheels if there is a deflation.
I've done at least one t/o and two ldgs on 3 mainwheels.
The trick is to keep an eye on the brake temps. If one is still at the bottom after you landed- you got a flat! It may well look normal-even if you kick it-on the walkround so that low brake temp is the only clue you get that you arte about to do a sector with three working tyres!!