The trip to the IOM from EGTO is very straightforward. EGTO - BPK - DTY - LIC - EGNR - DCT. Need to talk nicely to Luton for the BPK/DTY leg. Don't forget you need to arrange handling, I suggest Manx Aero Club is favourite and they may still have a car that they will rent to you for a small fee.
Over the years, I have found an IMC rating to be very useful to escape from the Island which seems to have its own weather system. I now use BA in the winter as its cheaper and more reliable!