At the time of discovering the dealy, your colleague should have called crewing to inform them that she had reported and also spoken to the Captain so that her duty time started at 0445Z.
Does your company have a policy that you call the delay line prior to every flight? That she didn't call it could be a problem as technically crewing have attempted to inform her.
Also, if your colleage is a member of the Union I suggest that she gets in touch with them.
Technically she is legal for the duty the next day (at least by the journey log of the flight she just did), though if she went fatigued 1.5 hours prior to the report for the next duty, then she does have exceptional circumstances from the previous day. Again, it all depends (unfortunately) if she is permanent.
I would also reccomend Chirping this - it's passed on to the airline for response and also to the CAA and remains confidential.