Three options come to mind:
1. Use a fuel alternate whenever possible to reduce the 5% to 3%
2. Use DPP (Decision Point Planning) when possible
3. Use No ALTN planning when possible.
These will all give some saving in fuel, and of course can be used together in combination.
Also remember that sometimes a slightly longer route may give fuel benefits due winds, and overflight charges.
Is this the sort of thing you are looking for.
Regards Expat