It's not surprising that other posters have expressed concern about the likely results of an incident like this on a transoceanic flight.
For the record, UPS's Web site clearly states that UPS will not transport packages with contents determined by the US Department of Transportation to be "hazardous materials" beyond the 50 states and Puerto Rico.
It's worthwhile noting that if this incident does indeed lead to UPS's first hull loss, then it will be the first aircraft loss in the company's 98-year history.
Well done to the crew. I do hope they are able to put their feet up for a while and enjoy a refreshment or two before their next roster.