Have the crew takeoff from a runway where conditions are at takeoff minimums. Have the wind set 90deg to the runway at 15kts. Have a runway with an ILS for both ends.. ie runway 09-27 with an ILS serving each runway.
Clear the crew for takeoff and give routine vectors away from the airport generally on the runway heading. when the crew is about 40 miles from the airport, introduce a cabin smoke/fire. No other airports are available for landing. The airfield they just departed is now down to CatIIIB limits.
IF the crew is alert, they will put on the masks and begin working through the smoke/fire problem. IF they departed on 27, they are now west of the field and if they are quick thinking, they will declare an emergency, request the field turn on the ILS for 09 and make an autoland with autobrakes set for max. This will land the airplane, and bring it to a stop on the runway where the crew can then go through an emergency evacuation.
This scenario presents a number of problems including workload, crew coordination, automation issues, reprogramming the FMS, etc. Introduced quickly enough, there will NOT be enough time to run all the checklists and at some point the crew will have to break off and land the airplane. When this happens, they will be well outside their comfort zone and will just have to make sure the airplane is configured for landing. Also, an alert crew will ignore the usual speed limits below 10,000ft (USA) and bolt for the field. The test here is to arrive at the field able to land and not with so much speed they have to go around.
At 'my old house' we had the Capt run the checklists in emergency abnormals with the F/O flying the airplane. This works very well in that you have 1 person involved with the checklist and making decisions with the other pilot programming/monitoring the autopilot.
The scenario can take as little as :20 to run when done properly. Oddly enough we had some crews ask for holding instructions for time to complete checklists. Others (me included) just headed for the field, did as many checklist items as they could, landed and evacuated.
Good luck.