Our company flys classic 747's. However, we use a bit of wisdom from the -400 in our thinking. Above 80 knots, the front C&W panel is blanked out. Boeing thinks that anything on that panel is not worth rejecting for over 80 knots. So, we keep this in our thinking while in the sim and try to use it on the line.
So, that leaves an engine failure or a fire to think about, or something really obscure.
At V-1, our hands come off the throttles, feet off the brakes.
Boeing says that the v-1 decision can be made at v-1 and that allows for the few seconds it takes to make a decision.
Well, our policy is , at V1, hands come off the throttles, were going. Our OPS system has made things very scary. it basically turns every runway into a balanced field, except for when your really light.
Don't make up your own rules, that will get you into trouble!
I'm just a line pilot, and I like to learn from other folks misfortunes.