For a normal GA spamcan (say 100kt) max drift is half the wind.
So if the crosswind component is 20kt, the required heading correction will be 10 degrees.
For 150kt is it a third of the wind.
The above are as close to the precise slide rule (

) figure as any human can hold a heading
If you go much slower then it becomes pretty critical, but then you probably won't be going very far.
If you are going much faster, you will have proper methods of navigation, like a GPS.