If you're familiar with max drift (MD) just use the DI as a representation of the sine function.
Imagine a horizontal line from the centre of the DI to the edge, think of this as being of length MD. Turn onto your track, find the wind on the outside of the DI and mentally drop a line straight down onto the MD line so that it divides it into two parts, the proportion of the line between the cente and where the vertical line touches it is the proportion of max drift on that track, turn towards the wind by that fraction of MD and then add variation. Sounds complex but it takes about 10 seconds and very little brain - 100% accurate.
For head/tail wind use the same process but this time the vertical radius of the DI represents the windspeed. Once you have the head/tail wind component subtract/add to your TAS to give groundspeed.
Convert distance and groundspeed to time either by using a scale, by the fact that you will travel 10% of your groundspeed in 6 minutes or by estimates based on easy speeds (120kts: time= 0.5 x distance, 100kts: time =0.6x distance, etc).
This whole thing takes less than a minute, very little brain and is as accurate as a wizz wheel. Once you've practised a little you may never use a wizz wheel again.
HFD