I did ME-twin IR-single CPL as that is the way the school taught it. You will do well to pass the IR in 40 sim & 15 a/craft even after doing the ME training, unless you're a bit of an ace. Even the young guys who were really on the ball took around 25 hrs in the a/craft, with 30 in the sim. (Even guys converting a FAA IR were taking about 15-20 hrs in the a/craft).
The advantage was that I found the CPL a dawdle, but overall you won't probably won't make a cost saving. A twin CPL though, will give you more multi hrs and probably make you slightly more employable.